Denosumab More Effective Than Zometa in Prostate Cancer Patients with Bone Metastases (02-10-2010)

Among men with bone metastases from prostate cancer, the investigational drug denosumab was more effective than Zometa® (zoledronic acid) at delaying or preventing bone complications such as fracture. Results from this Phase III clinical trial will... Continue Reading

Coffee May Reduce Risk of Lethal and Advanced Prostate Cancer (12-18-2009)

Men who drink coffee may have a reduced risk of developing lethal and advanced prostate cancer. These results were presented at the 2009 AACR Frontiers in Cancer Prevention Research conference. Prostate cancer is the most common cancer (other than skin... Continue Reading

Minimally Invasive Prostate Surgery May Have Pros and Cons (10-14-2009)

Laparoscopic radical prostatectomy, a less invasive surgical procedure that has gained in popularity in recent years, appears to result in shorter hospital stays, fewer blood transfusions, and fewer postoperative respiratory complications than open, retropubic... Continue Reading

Addition of Androgen Deprivation Therapy Improves Survival with Locally Advanced Prostate Cancer (10-8-2009)

In men with locally advanced prostate cancer, the addition of androgen deprivation therapy to radiation therapy improves overall and progression-free survival without substantially affecting cardiovascular mortality. These results, based on close to 10... Continue Reading

Hormone Therapy in Prostate Cancer Increases Risk of Heart Disease (10-6-2009)

Hormone therapy used to treat men with advanced prostate cancer may lead to an increased risk of heart disease, according to the results of a study presented on September 22, 2009 at Europe’s largest cancer congress, ECCO 15-ESMO 34, in Berlin.[1] Prostate... Continue Reading

Obese Men Have Higher-grade and Larger Prostate Cancers (09-21-2009)

Obese men with prostate cancer have higher-grade, larger tumors, according to a study published in Prostate Cancer and Prostatic Diseases.[1] Body mass index (BMI) is a measurement of height and weight utilized to indicate body fat. A BMI between 18.5... Continue Reading

Infection Linked with Aggressive Prostate Cancer (09-16-2009)

The sexually transmitted infection Trichomonas vaginalis may increase the risk of advanced prostate cancer. These results were published in the Journal of the National Cancer Institute. Trichomonas vaginalis is a single-celled protozoan parasite. It is... Continue Reading

Study Explores Overdiagnosis of Prostate Cancer (09-10-2009)

For every man who benefits from prostate cancer screening, many more are diagnosed and treated unnecessarily. The extent of this “overdiagnosis” of prostate cancer was explored in a study published in the Journal of the National Cancer Institute. Each... Continue Reading

Watchful Waiting Appropriate for Some Men with Prostate Cancer (09-8-2009)

Survival among men who choose to delay prostate cancer treatment appears to be similar to survival among men who choose immediate treatment. These results were published in the Journal of Clinical Oncology. Men with early-stage prostate cancer have the... Continue Reading

Androgen-deprivation Therapy Increases Risk of Death in Men with Heart Disease (09-1-2009)

Among men with prostate cancer and a history of heart attack or congestive heart failure, receipt of androgen-deprivation therapy prior to radiation therapy increased the risk of death. These results were published in the Journal of the American Medical... Continue Reading

Clodronate Improves Survival in Metastatic Prostate Cancer (08-25-2009)

Clodronate reduces the risk of death by 23% in men with metastatic prostate cancer, according to the results of a study published in The Lancet Oncology.[1] Clodronate belongs to a class of drugs called bisphosphonates. Bisphosphonates are agents used... Continue Reading

Denosumab Reduces Fractures in Non-metastatic Prostate Cancer (08-11-2009)

Men undergoing androgen deprivation therapy (ADT) for non-metastatic prostate cancer experienced a 62% reduction in risk of vertebral fractures when treated with denosumab compared to men treated with placebo, according to the results of a study published... Continue Reading